A 19-year-old North Lynn man has been charged with murder and assisting an offender.
A second man, aged 24, of Wisbech, has also been charged with murder.
The charges relate to the death of a 23-year-old Wisbech man who died after being stabbed in the leg last September. Both men charged with murder were originally arrested last year but were released under investigation.
They were re-arrested on Wednesday and were set to appear in court yesterday.
No further action was taken against four other men arrested last year in connection to the incident.