Police are appealing for witnesses after a fatal crash on the A1122 at Stradsett.
The collision, involving a black Proton and a red Volvo lorry, happened at around 10am on Wednesday.
The driver of the car, in his 60s, was pronounced dead at the scene and the passenger, a woman in her 70s, later died in hospital.
Anyone with information is asked to contact Sgt Peter Howlett at the Roads and Armed Policing Team at Swaffham.
Email firstname.lastname@example.org or call 101 and quote incident 121 of 21/10/20.